Proefschrift

Figure B.19: The projections of all 10 , 000 initial tumor compositions used in testing the clinically feasible protocols. ( x T + , x T P )-space in the left panel, ( x T + , x T − )-space in the center panel, and ( x T P , x T − )-space in the right panel. Figure B.20 shows the projections of 1139 initial tumor compositions that did not breach the patient viability constraint during the simulation under adaptive therapy. Figure B.20: Projections of the initial tumor compositions of the 1139 patients that survived under adaptive therapy. ( x T + , x T P )-space in the left panel, ( x T + , x T − )-space in the center panel, and ( x T P , x T − )-space in the right panel. Figure B.21 shows the projections of 912 initial tumor compositions that did not breach the patient viability constraint during the simulation under titration with Λ( t 0 ) = 1 and target volume is the initial tumor volume, V a . 151