Proefschrift

Freischel AR, Damaghi M, Cunningham JJ , Ibrahim-Hashim A, Gillies RJ, Gatenby RA, and Brown JS. (2021) Frequency dependent interactions determine outcome of competition between two breast cancer cell lines. Scientific Reports. Cunningham JJ , Thuijsman F, Peeters R, Viossat Y, Brown JS, Gatenby RA. and Stanˇkova´ K. (2020) Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer. PloS One. Whelan CJ, and Cunningham JJ (2020) Resistance is not the end: lessons from pest management. Cancer Control. Cunningham JJ (2019) A call for Integrated Metastatic Management. Nature Ecology and Evolution. Howard R, Scheiner A, Cunningham JJ , and Gatenby RA. (2019) Cytoplasmic convection currents: implications of intracellular temperature gradients. PLoS Computational Biology. Cunningham JJ , Brown JS, Gatenby RA, and Stanˇkova´ K. (2018) Optimal control to develop therapeutic strategies for metastatic castrate-resistant prostate cancer. Journal of Theoretical Biology. Zhang J, Cunningham JJ , Brown JS, and Gatenby RA. (2017) Integrating evolutionary dynamics into treatment of metastatic castrate resistant prostate cancer. Nature Communications. You L, Thuijsman F, Cunningham JJ , Gatenby RA, Zhang J, and Stanˇkova´ K. (2017) Spatial vs. non-spatial eco-evolutionary dynamics in tumor growth model. Journal of Theoretical Biology. Brown JS, Cunningham JJ , and Gatenby RA. (2016) Aggregation effects and population-based dynamics as a source of therapy resistance in cancer. PLoS Computational Biology. Lloyd MC, Cunningham JJ , Bui MM, Gillies RJ, Brown JS, and Gatenby RA. (2016) Darwinian dynamics of intratumoral heterogeneity: random mutations or variable selection forces? Cancer Research. Brown JS, Cunningham JJ , and Gatenby RA. (2015) The multiple facets of Peto’s paradox: a life history model for the evolution of cancer suppression. Phil. Trans. R. Soc. B. Cunningham JJ , Brown JS, Vincent TL, and Gatenby RA. (2015) Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites. Evolution, Medicine, and Public Health. Gatenby RA, Cunningham JJ , and Brown JS. (2014) Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations. Nature Communications. 161