Proefschrift

Contents Chapter 1 General introduction and thesis outline 9 Part I Current treatment strategies Chapter 2 Systematic review of resection rates and clinical outcomes after FOLFIRINOX-based treatment in patients with locally advanced pancreatic cancer Annals of Surgical Oncology 2016 21 Chapter 3 Treatment strategies and clinical outcomes in consecutive patients with locally advanced pancreatic cancer: a multicenter prospective cohort 37 European Journal of Surgical Oncology 2021 Chapter 4 The treatment and survival of elderly patients with locally advanced pancreatic cancer: post-hoc analysis in a multicenter registry Pancreatology 2021 57 Part II Outcome prediction Chapter 5 Predicting overall survival and resection in patients with locally advanced pancreatic cancer treated with FOLFIRINOX: development and internal validation of two nomograms Journal of Surgical Oncology 2021 75 Chapter 6 Added value of intra-operative ultrasound to determine the resectability of locally advanced pancreatic cancer following FOLFIRINOX chemotherapy (IMAGE): a prospective multicenter study HPB (Oxford) 2019 93 Chapter 7 Occult metastases found during surgery in patients with presumed (borderline) resectable pancreatic cancer: development and external validation of a preoperative prediction model 109

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