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120 5 CHAPTER 5 12 | GOODARZI et al. from a time period in which the IOL rate has increased, which may have impacted the outcomes of this study. 4.5 | Conclusions This nationwide longitudinal retrospective cohort study in a healthy Dutch pregnant population showed that the probability of TM differed among subgroups of women depending on which determinants were considered and the number of determinants included. These results indicate that a routine approach using single determinants may result in underestimation or overestimation of probabilities of TM, leading to overuse or underuse of IOL. A VBHC strategy, addressing social inequity, and investing in better screening and diagnostic methods that employ an individualized and multi-determinant approach may be more effective at preventing fetal and neonatal mortality. ETHICAL APPROVAL Ethical approval was requested from the Medical Ethics Review Committee of VU University Medical Centre. The approval was waived because the Medical Research Involving Human Subjects Act did not apply to this study (reference number 2020140). DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from Perined. Restrictions apply to the availability of these data, which were used under license for this study. Data are available from the author(s) with the permission of Perined. ORCID Bahareh Goodarzi https://orcid.org/0000-0002-9758-1299 Neel Shah https://orcid.org/0000-0002-8971-7627 REFERENCES 1. Knight HE, Cromwell DA, Gurol-Urganci I, Harron K, van der Meulen JH, Smith GCS. Perinatal mortality associated with induction of labour versus expectant management in nulliparous women aged 35 years or over: an English national cohort study. PLoS Medicine. 2017;14(11):e1002425. doi:10.1371/journ al.pmed.1002425 2. Flenady V, Koopmans L, Middleton P, et al. Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis. 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