Summary 135 In the study reported in chapter 8, the cost-effectiveness and the cost-utility of the PWB protocol was compared to the standard RWB protocol from both a societal and a hospital perspective. This prospective comparative cohort study included surgically treated trauma patients with peri- and/or intra-articular fractures of the lower extremities followed by PWB or RWB. Costs, Activities of Daily Living (ADL) and quality of life were measured during 26 weeks (at baseline, 2, 6, 12 and 26 weeks postsurgery). Cost per quality adjusted life year (QALY) gained (cost-utility) and cost per ADL or Life Years (cost-effectiveness) were estimated. This study included 106 trauma patients (N=53 in both the PWB and the RWB-group). There were no group differences in baseline characteristics. Costs were lowest for the PWB group (€9,379.45 vs. €9,836.96) during 26 weeks post-surgery.