4 105 Neural and affective responses to prolonged eye contact with parents and unfamiliar others in depressed and non-depressed adolescents SUPPLEMENT S4.3 fMRI data acquisition MR images were acquired at the LUMC using a Philips 3.0T Achieva MRI scanner equipped with a SENSE-32 channel head coil. For the eye contact task, T2*-weighted echo planar imaging was used with the following parameters: TR = 2200 ms, TE = 30 ms, flip angle = 80°, FOV 220 × 220 × 114.7 mm, matrix size = 80 × 80, voxel size = 2.75 mm3, slice gap = 0.275 mm, 38 transverse slices in descending order. As subjective response ratings were self-paced, number of volumes varied between participants (run 1: M = 146.6, SD = 8.2, range = – 126 165; run 2: M = 147.7, SD = 8.7, range = 172 – 129). A structural 3D T1 scan was acquired with the following parameters: TR = 7.9 ms, TE = 3.5 ms, TI = 820 ms, flip angle: 8°, voxel size = 1 mm3, 155 transverse slices FOV 195.8 × 250 × 170.5 mm, matrix size = 228 × 177, duration: 4:11 min. The first five volumes were discarded to allow for equilibration of T1 saturation effects. A b0 field map was acquired with the following parameters: TR = 200 ms, TE = 3.2, matrix size = 80 × 80, with 38 slices, voxel size = 2.75 mm3. The task was programmed and presented electronically using E-prime 2.0 (Tools Psychology Software, 2012) and participants could see the task through a mirror attached to the head coil. Foam inserts were used to restrict head motion if necessary.
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