5 123 Neural signatures of parental empathic responses to imagined suffering of their adolescent child Data were collected in the context of the RE-PAIR study: “Relations and Emotions in ParentAdolescent Interaction Research”. The RE-PAIR study uses a multi-method and multi-informant approach and examines the relation between parent-child interactions and adolescent depression by comparing families with an adolescent with a current major depressive disorder or dysthymia to families with an adolescent without psychopathology. The present study focused on neuroimaging data collected from parents of healthy adolescents in this larger study. Families were included in this study if the adolescent and at least one of the parents/caregivers were willing to participate in the study and had a good command of the Dutch language. Further inclusion criteria for the adolescents included being aged between 11 and 17 years, living with at least one of their parents/caregivers, no diagnosis of a (neuro)psychiatric disorder in the two years leading up to the study, and no lifetime diagnoses of major depressive disorder or dysthymia. Additionally, exclusion criteria for the functional magnetic resonance imaging (MRI) part of the study were incompatibilities with the MRI scanner. The study was approved by the medical ethical committee of the Leiden University Medical Centre (LUMC) (P17.241) and was performed in accordance with the declaration of Helsinki and the Dutch Medical Research Involving Human Subjects Act (WMO).
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