5 133 Neural signatures of parental empathic responses to imagined suffering of their adolescent child Figure 5.3 Overview of regions of interest in cognitive and affective empathy networks and results showing how the perspective of imagined suffering modulated activity within the cognitive, but not the affective, empathy network. A) Schematic overview of ROI spheres in affective empathy network in red (bilateral AI and aMCC) en cognitive empathy network in green (bilateral TPJ, bilateral dmPFC and vmPFC). B) Parameter estimates of BOLD-responses in ROIs in the cogntive empathy network where the perspective of imagined suffering impacted on activity in the regions (i.e., main effect of ‘perspective’). C) Parameter estimates of BOLD-responses in ROIs in the affective empathy network. No main effect of ‘perspective’ was found in bilateral AI and aMCC. All ROI results were Bonferroni corrected for the number of tests (p <.05/8). Error bars represent standard error of the mean. Significant p-values <.05 were indicated by *, p <.01 by **, and p <.001 by ***.
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