CHAPTER 3.2 146 Supplementary table 1. Quasi-Poisson regression analysis with (i) only time, (ii) time, sex and age and (iii) age and an interaction term between time and sex Unadjusted model Model with time, sex and age Model with age and interaction term between sex and time Predictors Incidence Rate Ratios CI p Incidence Rate Ratios CI p Incidence Rate Ratios CI p Intercept 0.56 0.35 – 0.88 0.016 0.02 0.02 – 0.03 <0.001 0.02 0.02 – 0.03 <0.001 Time 1.00 0.93 – 1.08 0.968 0.99 0.982-0.996 0.003 0.99 0.98 – 1.00 0.102 Time: Women 0.99 0.98 – 1.01 0.347 Women 0.77 0.74 – 0.80 <0.001 0.80 0.73 – 0.88 <0.001 Age, in years (ref =20-<25) 25-<30 1.79 1.26 – 2.57 0.002 1.79 1.26 – 2.57 0.002 30-<35 3.22 2.33 – 4.54 <0.001 3.22 2.33 – 4.53 <0.001 35-<40 5.77 4.25 – 8.01 <0.001 5.77 4.25 – 8.00 <0.001 40-<45 10.85 8.10 – 14.87 <0.001 10.85 8.10 – 14.86 <0.001
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