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3.3 Ten-year trends for heart failure outcomes 181 Supplementary table 2. Multivariable Poisson regression analysis for 30-day readmission, in-hospital, 30-day and 1-year mortality rates with interaction term between time and ethnicity to determine statistical significance of trend differences by ethnicity 30-days readmission In-hospital mortality 30-day mortality 1-year mortality Rate ratio CI p Rate ratio CI p Rate ratio CI p Rate ratio CI p (Intercept) 0.16 0.15 – 0.17 <0.001 0.06 0.06 – 0.07 <0.001 0.11 0.10 – 0.12 <0.00 1 0.30 0.29 – 0.31 <0.00 1 Time 1.02 1.01 – 1.02 <0.001 0.93 0.91 – 0.94 <0.001 0.97 0.96 – 0.97 <0.00 1 1.00 0.99 – 1.00 0.231 Time: Chinese 1.00 0.98 – 1.01 0.578 1.01 0.99 – 1.04 0.349 1.00 0.99 – 1.02 0.858 1.00s 0.99 – 1.01 0.738 Time: Indian 1.00 0.98 – 1.02 0.924 0.98 0.94 – 1.01 0.195 0.99 0.97 – 1.02 0.504 1.01 1.00 – 1.03 0.010 Time: Others 1.03 1.01 – 1.05 0.002 1.00 0.98 – 1.03 0.920 0.98 0.97 – 1.00 0.091 0.99 0.98 – 1.00 0.021 Malay Reference Chinese 1.14 1.05 – 1.24 0.002 1.14 0.98 – 1.31 0.089 1.07 0.97 – 1.18 0.155 0.96 0.91 – 1.01 0.156 Indian 1.11 1.01 – 1.23 0.038 0.93 0.75 – 1.14 0.474 0.83 0.73 – 0.96 0.010 0.80 0.74 – 0.86 <0.00 1 Others 0.68 0.60 – 0.77 <0.001 1.90 1.63 – 2.22 <0.001 1.42 1.26 – 1.59 <0.00 1 1.03 0.96 – 1.11 0.369 Female Reference Male 1.16 1.13 – 1.19 <0.001 1.02 0.97 – 1.08 0.429 1.11 1.07 – 1.15 <0.00 1 1.17 1.15 – 1.19 <0.00 1

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