Generalizability of HFrEF trials 37 Supplementary table 1 (continued). Characteristics, inclusion and exclusion criteria of trials Study name BEAUTIFUL CONFIRM-HF FAIR-HF PANTHEON SHIFT Screening serum ferritin <100 ng/mL OR 100-300 ng/mL with transferrin saturation <20%. Screening ferritin below 100 μg/L, or below 300 μg/L when transferrin saturation (TSAT) is below 20% (re-screening is possible after 4 weeks for patients with borderline higher ferritin concentrations or borderline TSAT percentage if the investigator feels that levels might drop below cut-off in the near future. Resting blood pressures less than or equal to 160 mm Hg (systolic) and less than or equal to 100 mm Hg (diastolic at the disappearance of sounds, Korotkoff phase V). Adequate veins for repeated blood sampling and intravenous administration of investigational drug. Negative pregnancy test and use of adequate contraceptive methods for women of childbearing potential. Capable of completing the 6MWT. Capable of completing the 6 MWT. 2.1
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