2.2 Eligibility for HFrEF trials 67 Table 3. Median eligibility by trial characteristic n Median score p-valuea Start year 0.03 1985-2005 42 0.40 2006-2010 36 0.15 2011-2015 48 0.14 2016-2022 37 0.19 Intervention type <0.001 Drug 102 0.25 Device 33 0.09 Procedural/ diagnostic 10 0.09 Behavioural/ dietary 13 0.40 Biological 5 0.05 Primary funder 0.01 Industry 78 0.13 Academic/ healthcare institution 53 0.27 NIH/ government agency 26 0.23 Otherb 6 0.19 Trial size ≤50 41 0.23 0.5 51-150 36 0.13 151-400 40 0.16 401-8500 40 0.19 missing 6 NIH, National Institutes of Health, U.S. Department of Health and Human Services. a, Kruskal Wallis rank sum test b, Includes managed care or non-profit organizations, individual investigators and networks.
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