2.2 Eligibility for HFrEF trials 77 SUPPLEMENTARY MATERIAL Supplementary table 1. And equivalent terms Equivalent terms Heart failure Heart failure, myocardial failure, cardiac failure, ventricular failure, heart decompensation, myocardial decompensation, cardiac decompensation, ventricular decompensation, CHF, HFrEF, HFpEF, HFmrEF Supplementary Table 2. Patient characteristics for BIOSTAT-CHF and ASIAN-HF registries Patient characteristic BIOSTAT-CHF (n=2545) ASIAN-HF (n=4868) n (%) n (%) Age(years) Mean (SD) 68.7 11.8 60.4 12.9 Median (IQR) 70 61.1, 77.5 61 52, 69 Men 2991 70.3 3799 78.0 BMI (kg/m2) Median (IQR) 27.1 24.1, 30.6 24.2 21.7, 27.5 NYHA class I 166 7.1 621 14.1 II 1189 50.9 2459 55.7 III 842 36.1 1155 26.1 IV 138 5.9 183 4.1 LVEF (%) Mean (SD) 28.1 7.12 27.1 7.1 Median (IQR) 30 24.0, 35.0 27.4 21.9, 33.0 Clinical parameters, median (IQR) Systolic blood pressure (mmHg) 120 110,135 117 105, 130 Diastolic blood pressure (mmHg) 71 65.0,80.0 70 63, 80 Heart rate (bpm) 75 65.0,88.0 78 69, 88 Sinus rhythm 1404 55.2 3260 70.4 Heart failure history Prior HF hospitalization in past year 1254 29.5 In past 6 months 1611 38.8 Ischaemic heart disease 2486 67.8 2507 51.5 Medical history AF 1085 42.6 858 17.6 MI 1110 43.6 1444 29.7
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