90 CHAPTER 3.1 Table 1. Baseline characteristics compared between RCT populations, RCT-eligible registry population, and RCT-ineligible registry population, stratified by sex. RCT RCT-eligible registry RCT-ineligible registry Females Males pvalueb Females Males pvalueb Females Males pvalueb n 3 663 13 254 8294 17 810 6 290 14 520 Demographics and lifestyle, mean (S) or % Age (years) 66.3 (9.9) 62.8 (9.9) *** 73.9 (9.1) 69.8 (12.2) *** 76.7 (9.7) 73.8 (9.3) *** Smoking history *** *** *** Never 72.4% 29.0% 53.0%a 35.50%a 57.0% 37.80% Previous/Curre nt 27.6% 71.0% 47.0%a 64.50%a 43.0% 62.20% Clinical parameters, mean (SD) or % HF duration (months) 42.4 (58.4) 41.6 (58.7) 21.0 (58.6) 30.8 (58.8) *** 21.1 (32.2) 24.4 (31.2) *** SBP (mmHg) 126.5 (14.9) 124.9 (14.9) *** 126.4 (16.0) 123.7 (20.5) *** 125.7 (17.1) 124.0 (15.2) *** BMI (kg/m2) 28.6 (5.5) 28.2 (4.6) *** 26.6 (6.5) 27.2 (6.0) *** 25.6 (4.7) 26.0 (4.3) *** Creatinine (μmol/L) 90.3 (33.9) 101.6 (41.3) *** 90.6 (37.6) 103.4 (38.2) *** 108.9 (0.3) 129.7 (60.6) *** LVEF (%) *** *** *** 0-29 28.7% 32.6% 47.0% 56.1% 43.0% 48.6% 30-39 67.4% 66.6% 53.0% 43.9% 57.0% 51.4% 40+ 3.9% 0.8% 0.0% 0.0% 0.0% 0.0%
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